The summary of reviews offers a recent look at what studies are reporting on the benefits of exercise. It is important to reinvestigate findings periodically to ensure the most accurate information and determine what is no longer true. Not only is it important that these reviews are finding rewards in almost all treatments of exercise on muscle-wasting conditions, but also that there are changes in the quality of life in people with these chronic conditions. This review puts into perspective that not only is exercise for healthy people to maintain their vigor but that it is something for everyone that will benefit well-being and possibly delay morbidity.